As someone who travels every week (and has a Blackberry e-mail umbilical cord attached), I find the best way to vacation -- while not letting the e-mail pile up -- is to leave the laptop at home. Then find the nearest cybercafe and check it once every day or two, but not reply to any e-mails; just sort, so I know what I'll be facing when I return.

Replying invites an early end to any vacation. But it is darned hard to avoid doing so.

Yea, I bring my laptop with me when I go out of state and usually can find a cafe or somewhere that has wireless connectivity.